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PREB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 10146-2-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16806343

  • 112.71€ / 20µL

Expédition estimée
10-03-2021

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Description

Description

Prolactin (PRL) expression in the pituitary is limited to specific cells. Pit-1 is a pituitary specific transcription factor that plays an important role in PRL expression, both in mature organism and during development. The PRL promoter contains numerous Pit-1 binding sites and these sites have been implicated in both basal level and kinase-mediated gene expression. The most proximal of these binding sites, termed 1P, has been shown to direct a response to numerous signals, such as cAMP and various G-proteins. A novel protein, termed PREB (prolactin regulatory element binding protein), has been recently identified that regulates PRL gene expression through the 1P site, though it contains no discernable DNA-binding motif. Recent studies suggest that PREB is encoded by a single-copy gene in both mice and humans and exhibits nuclear accumulation in pituitary cells. Evidence suggests that PREB is a novel transcription factor that assists in PRL expression whether alone, or in concert with Pit-1.
Spécification

Spécification

PREB
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9HCU5, Q9WUQ2
PREB, SEC12
Rabbit
IgG
20 μL
-20°C
Primary
10113, 50907
Immunoprecipitation, Immunocytochemistry, Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
PREB
Liquid
Preb
PREB Fusion Protein Ag0202
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Vidéos
FDS
Documents