missing translation for 'onlineSavingsMsg'
Learn More

PSMA Monoclonal Antibody (GCP-05), PE, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen MA110336

Code produit. 12302353

  • 532.00€ / 100µg

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!

Découvrez plus d'offres spéciales
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Description

Description

This antibody recognizes an extracellular domain, preferentially in native form, of glutamate carboxypeptidase II.

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

PSMA
Monoclonal
0.1 mg/mL
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Q04609
FOLH1
amino acids 44-750 of human GCPII
100 μg
Primary
Human
Antibody
IgG1
Flow Cytometry
GCP-05
PE
FOLH1
Cell growth-inhibiting gene 27 protein; FGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1; FOLH; Folh1; Folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; GIG27; glutamate carboxylase II; glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; mopsm; Naalad; NAALAD1; NAALAdase; NAALADase I; N-acetylated alpha-linked acidic dipeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen; prostate specific membrane antigen variant F; prostate-specific membrane antigen; Prostate-specific membrane antigen homolog; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase
Mouse
Size-exclusion chromatography
RUO
2346
4° C, store in dark, DO NOT FREEZE!
Liquid
Suggestions de produits

Suggestions de produits

Vidéos
FDS
Documents

Documents

Certificats
Promotions

Promotions