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PTPN13 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 25944-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16804485

  • 112.71€ / 20µL

Expédition estimée
03-03-2021

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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Spécification

Spécification

PTPN13
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q12923
FAP 1, hPTPE1, PNP1, PTP BAS, PTP BL, PTP E1, PTP1E, PTPL1, PTPLE, PTPN13
Rabbit
IgG
20 μL
-20°C
Primary
5783
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PTPN13
Liquid
PTPN13
PTPN13 Fusion Protein Ag22854
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Vidéos
FDS
Documents