missing translation for 'onlineSavingsMsg'
Learn More

RAP1GAP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14229-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

 Afficher plus de versions de ce produit

Code produit. 16802774

  • 329.85€ / 150µL

Expédition estimée
15-06-2021

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Rap1GAP specifically stimulates GTP hydrolytic activity of the monomeric G protein Rap1. Physical interaction between G alpha z, a member of the Gi family of trimeric G proteins, and Rap1GAP blocks the ability of regulators of G protein signaling to stimulate GTP hydrolysis of the alpha subunit, and also attenuates the ability of activated G alpha z to inhibit adenylyl cyclase. Rap1GAP is expressed in the brain, kidney and pancreas and may act as a signal integrator to coordinate and/or integrate Gz signaling and Rap1 signaling in cells. A novel isoform of Rapl GTPase-activating protein, designated Rap1GAPII, binds specifically to G alpha z. Stimulation of the Gi-coupled M2 Muscarinic receptor translocates Rap1GAPII from the cytosol to the membrane and decreases the amount of GTP-bound Rap1, resulting in the activation of ERK/MAPK.
Spécification

Spécification

RAP1GAP
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
A2ALS5, P47736
KIAA0474, RAP1 GTPase activating protein, RAP1GA1, RAP1GAP, RAP1GAP1, RAP1GAPII, RAPGAP
Rabbit
IgG
150 μL
-20°C
Primary
110351, 313644, 5909
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
RAP1GAP
Liquid
Rap1gap
RAP1GAP Fusion Protein Ag5469
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents