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enQuireBio™ Recombinant Human Leptin tA Protein
A cDNA sequence encoding the Leptin tA was constructed and used to recombinantly synthesize the protein.
Marque: enQuireBio™ QP10766-5ug
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Spécification
Leptin tA Protein | |
Research Use Only | |
Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher. | |
Human | |
Untagged | |
Greater than 98.0% as determined by: (a) Gel filtration analysis. (b) Analysis by SDS-PAGE. |
5 μg | |
< 1.0 EU per ug protein as determined by the LAL method. | |
Recombinant Protein | |
E. coli | |
The protein was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003mM NaHCO3. |
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