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ACROBiosystems Rhesus macaque CD4 Protein, Fc Tag

Marque:  ACROBiosystems CD4-C5256-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15876177

  • 252.20€ / 100µg
Date d’expédition estimée: 07-01-2022

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Description

Description

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67.0 kDa. The protein migrates as 67-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Rhesus macaque CD4, Fc Tag (CD4-C5256) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8).
-20°C
CD4
Fc Tag
HEK293
Rhesus macaque
67.0 kDa
100 µg
Lys 26 - Trp 390
CD4,CD4mut,LEU3
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
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