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Rubicon Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 55157-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16836635

  • 121.38€ / 20µL
Expédition estimée: 06-10-2022
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Description

Description

Two Beclin-1-interacting proteins, the run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon) and ATG14L, reciprocally regulate autophagy at different stages. Knockdown of Rubicon caused enhancement of autophagy while that of ATG14L caused a defect in autophagosome formation. Rubicon functions as part of a Beclin-1-PIK3C3-containing autophagy complex and is also an essential, positive regulator of the NAPDH oxidase complex. Upon microbial infection or TLR2 activation, Rubicon interacts with the CYBA subunit of the NAPDH oxidase complex, leading to a burst of reactive oxygen species and inflammatory cytokines.
Spécification

Spécification

Rubicon
Polyclonal
Unconjugated
RUBCN
Baron, KIAA0226, Rubicon
Rabbit
Antigen Affinity Chromatography
RUO
9711
-20°C
Liquid
Western Blot
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q92622
RUBCN
Peptide
20 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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