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ACROBiosystems SARS-CoV-2 Nucleocapsid protein (D3L, R203K, G204R, S235F), His Tag

Marque:  ACROBiosystems NUN-C52H8-100ug

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17266360

  • 456.19€ / 100µg
Expédition estimée: 10-01-2023
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Description

Description

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.4 kDa. The protein migrates as 30-35 kDa and 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

QHO62115.1
>90% as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52H8) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). D3L/ R203K/ G204R/ S235F were identified in the SARS-CoV-2 variant (known as 20 B/501 Y.V1, VOC 202012/01, or B0.1.1.7 lineage) which emerged in the United Kindom.
-20°C
Nucleocapsid protein
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
SARS-CoV-2
47.4 kDa
100 µg
Met 1 - Ala 419
Nucleocapsid protein,NP,Protein N,COVID-19
Unconjugated
PBS, pH7.4
HEK293
Viral Proteins
Vidéos
FDS
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