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SSEA1 Monoclonal Antibody (MEM-158), APC, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen MA110106

Code produit. 12332133

  • 382.00€ / 100 pièces

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Description

Description

This antibody will not cross-react with porcine, bovine or sheep.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

SSEA1
Monoclonal
APC
FUT4
FUTIV, Lewis X, SSEA-1
Mouse
Size-exclusion chromatography
RUO
2526
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
MEM-158
TBS with 0.2% BSA and 15mM sodium azide; pH 8
P22083
FUT4
Human granulocytes
100 Tests
Primary
Human
Antibody
IgM
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