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T-bet Monoclonal Antibody (eBio4B10 (4B10)), eFluor™ 450, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Affymetrix eBioscience 48-5825-80

112.00 EUR valable jusqu'au 2024-03-29
Utilisez le code promo "21615" pour bénéficier de cette offre.



Informations supplémentaires : Poids : 0.01000kg

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Code produit. 16370924

  • 168.00€ / 25µg
Expédition estimée: 22-04-2024
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Description

Description

Description: The eBio4B10 monoclonal antibody reacts with mouse and human T-bet. T-bet is a Th1-specific T-box transcription factor critical to the development of the Th1 CD4+ T cell lineage. This is known based on the observations that T-Bet deficient mice have impaired Th1 cell development, and that ectopic expression of T-Bet results in development skewed to the Th1 lineage. T-Bet expression is induced by the Th1 cytokine IFN gamma, and T-Bet also regulates the expression of IFN gamma, likely, at least in part, through the modification of DNA accessibility and histone remodeling. In addition to IFN gamma, T-Bet is also known to regulate the expression of IL-12R beta and IL-2. Moreover, T-Bet plays a role in class-switch recombination in B-cells. Applications Reported: This eBio4B10 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio4B10 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells using the Foxp3/Transcription Factor Staining Buffer Set (Product No. 00-5523-00) and protocol. Please refer to Staining Intracellular Antigens for Flow Cytometry, Protocol B: One step protocol for intracellular (nuclear) proteins located at www.thermofisher.com/flowprotocols. This may be used at less than or equal to 0.5 μg per test.

T-bet Monoclonal antibody specifically detects T-bet in Human, Mouse, Rhesus Monkey samples. It is validated for Flow Cytometry.
Spécification

Spécification

T-bet
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9JKD8, Q9UL17
Tbx21
Affinity chromatography
RUO
30009, 57765, 694044
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
eBio4B10 (4B10)
eFluor 450
Tbx21
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Mouse
25 μg
Primary
Human, Mouse, Rhesus Monkey
Antibody
IgG1 κ
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