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TCF7L2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 13838-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16802234

  • 329.85€ / 150µL

Date d’expédition estimée: 18-06-2021

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Description

Description

TCF7L2, or TCF4, is a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. TCF7L2 has been implicated in glucose homeostasis through the regulation of pro-glucagon gene expression, which encodes glucagon-like peptide 1 (GLP-1). Genetic variants of TCF7L2 have been linked to type 2 diabetes, and it has specifically been shown to have an important role in the regulation of both beta-cell survival and function. Several splicing isoforms for TCF7L2 have been shown to be differentially expressed in tissues during cancer progression, and gene targeting studies indicate that TCF7L2 is required to maintain the crypt stem cells of the small intestine.
Spécification

Spécification

TCF7L2
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q924A0, Q9NQB0
HMG box transcription factor 4, hTCF 4, T cell factor 4, TCF 4, TCF4, TCF7L2, Transcription factor 7 like 2
Rabbit
IgG
150 μL
-20°C
Primary
21416, 679869, 6934
Immunoprecipitation, Western Blot
Unconjugated
TCF7L2
Liquid
Tcf7l2
TCF7L2 Fusion Protein Ag4786
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents