missing translation for 'onlineSavingsMsg'
Learn More

TH Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 25859-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

 Afficher plus de versions de ce produit

Code produit. 16804425

  • 112.71€ / 20µL

Expédition estimée
09-03-2021

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson′s disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.
Spécification

Spécification

TH
0.21 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P04177, P07101, P24529
TH, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, tyrosine hydroxylase
Rabbit
IgG
20 μL
-20°C
Primary
21823, 25085, 7054
Western Blot, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
TH
Liquid
TH
TH Fusion Protein Ag23075
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents