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TNNC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Spécification
| Antigène | TNNC1 |
|---|---|
| Concentration | 0.57 mg/mL |
| Applications | Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation |
| Classification | Polyclonal |
| Conjugué | Unconjugated |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
16801754
|
Proteintech
13504-1-AP-20UL |
20 μL |
140.00€
20µL |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
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|
16891744
|
Proteintech
13504-1-AP-150UL |
150 μL |
399.00€
150µL |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Troponin, working in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in the intracellular Ca2+ concentration. Troponin consists of three subunits: the Ca2+-binding subunit troponin C (TnC), the tropomyosin-binding subunit troponin T (TnT), and the inhibitory subunit troponin I (TnI). In response to beta-adrenergic stimulation of the heart, Ser23 and Ser24 of TnI (cardiac) are phosphorylated by PKA and PKC. This phosphorylation stimulates a conformational change of the regulatory domain of TnC, reduces the association between TnI and TnC, and decreases myofilament Ca2+ sensitivity by reducing the Ca2+ binding affinity of TnC (1-3).Spécification
| TNNC1 | |
| Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation | |
| Unconjugated | |
| Rabbit | |
| Rat, Human, Mouse | |
| P19123, P63316 | |
| 21924, 290561, 7134 | |
| TNNC1 Fusion Protein Ag4339 | |
| Primary | |
| -20°C | |
| TNNC1 |
| 0.57 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| CMD1Z, TN C, TNC, TNNC, TNNC1, troponin C type 1 (slow) | |
| Tnnc1 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |