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VEGFR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 20712-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16830285

  • 121.38€ / 20µL
Expédition estimée: 03-10-2022
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Description

Description

The antibody is specific to FLT4.

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
Spécification

Spécification

VEGFR3
Polyclonal
Unconjugated
FLT4
FLT 4, FLT4, FLT41, Fms like tyrosine kinase 4, fms related tyrosine kinase 4, LMPH1A, PCL, VEGFR 3, VEGFR3
Rabbit
Antigen Affinity Chromatography
RUO
14257, 2324
-20°C
Liquid
Western Blot
0.41 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P35916, P35917
FLT4
Peptide
20 μL
Primary
Mouse, Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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