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YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 24744-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16833235

  • 325.38€ / 150µL
Expédition estimée: 06-10-2022
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Description

Description

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5′-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.
Spécification

Spécification

YTHDF2
Polyclonal
Unconjugated
YTHDF2
CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2
Rabbit
Antigen Affinity Chromatography
RUO
51441
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9Y5A9
YTHDF2
YTHDF2 Fusion Protein Ag5922
150 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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