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Lovastatin, 97%, Thermo Scientific™
94.20€ - 347.00€
Identifiants chimiques
| CAS | 75330-75-5 |
|---|---|
| Formule moléculaire | C24H36O5 |
| Poids moléculaire (g/mol) | 404.55 |
| Numéro MDL | MFCD00072164 |
| Clé InChI | PCZOHLXUXFIOCF-BXMDZJJMSA-N |
| Synonyme | lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin |
| CID PubChem | 53232 |
| ChEBI | CHEBI:40303 |
| Nom IUPAC | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
| SMILES | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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15489537
|
Thermo Scientific Alfa Aesar
H52792.06 |
5g |
 96.10€ 94.20€ / 5g Économisez 1.90€ 1% de réduction |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
|
15499537
|
Thermo Scientific Alfa Aesar
H52792.14 |
25g |
354.00€ 347.00€ / 25g Économisez 7.00€ 1% de réduction |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsLovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.
Solubility
Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Identifiants chimiques
| 75330-75-5 | |
| 404.55 | |
| PCZOHLXUXFIOCF-BXMDZJJMSA-N | |
| 53232 | |
| (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
| C24H36O5 | |
| MFCD00072164 | |
| lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin | |
| CHEBI:40303 | |
| CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |
Spécification
| Lovastatin | |
| C24H36O5 | |
| lovastatin, mevinolin, mevacor, monacolin k, lovalip, altoprev, lovalord, mevinacor, nergadan, 6alpha-methylcompactin | |
| PCZOHLXUXFIOCF-BXMDZJJMSA-N | |
| (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate | |
| 53232 | |
| 404.56 |
| 75330-75-5 | |
| MFCD00072164 | |
| Soluble in DMSO (10mg/ml),ethanol (10mg/ml),methanol,chloroform,acetone,acetonitrile,DMF,and water (0.4 μg/ml). | |
| CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 | |
| 404.55 | |
| CHEBI:40303 | |
| 97% |
Sécurité et traitement
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P201-P202-P261-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c
H317-H351-H361d
missing translation for 'rtecsNumber' : EK7907000
missing translation for 'tsca' : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only
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