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(R)-(-)-Deprenyl hydrochloride, Thermo Scientific™
Selective MAO-B inhibitor; anti-Parkinsonian agent
75.40€ - 222.00€
Identifiants chimiques
| CAS | 14611-52-0 |
|---|---|
| Formule moléculaire | C13H18ClN |
| Poids moléculaire (g/mol) | 223.74 |
| Numéro MDL | MFCD00069299 |
| Clé InChI | IYETZZCWLLUHIJ-UTONKHPSSA-N |
| Synonyme | selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline |
| CID PubChem | 26758 |
| ChEBI | CHEBI:9087 |
| Nom IUPAC | hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride |
| SMILES | [H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|
15483899
|
Thermo Scientific Alfa Aesar
J61286.MD |
250mg |
75.40€
250mg |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
|
15473899
|
Thermo Scientific Alfa Aesar
J61286.03 |
1g |
222.00€
1g |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | |||||
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
Applications(R)-(-)-Deprenyl hydrochloride provides neuroprotection which may be relevant to Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and stroke. It is an inhibitor of MAO-B (monoamine oxidase-B) which demonstrates extensive neuroprotective effects shown to be uncorrelated with MAO-B inhibiting activity. It demonstrates protection of dopaminergic neurons from excitotoxicity mediated by NMDA activation. It also demonstrates decreases in apoptosis of PC12 neuronal cells accompanied with an induction of new protein synthesis through direct transcriptional and translational interaction, and reduced cell death and internucleosomal DNA degredation at concentrations too low to inhibit MAO-B.
Solubility
Soluble in water at 100mM
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Identifiants chimiques
| 14611-52-0 | |
| 223.74 | |
| IYETZZCWLLUHIJ-UTONKHPSSA-N | |
| 26758 | |
| hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride |
| C13H18ClN | |
| MFCD00069299 | |
| selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline | |
| CHEBI:9087 | |
| [H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C |
Spécification
| (R)-(-)-Deprenyl hydrochloride | |
| C13H18ClN | |
| 14,8428 | |
| Soluble in water at 100mM | |
| −12° (c=1 in Water) | |
| hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride | |
| 26758 | |
| 223.74 |
| 14611-52-0 | |
| MFCD00069299 | |
| selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline | |
| IYETZZCWLLUHIJ-UTONKHPSSA-N | |
| [H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C | |
| 223.74 | |
| CHEBI:9087 |
Sécurité et traitement
GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
H315-H319
missing translation for 'rtecsNumber' : DA0292500
missing translation for 'tsca' : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only
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Nom du produit
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