CAS RN 154447-36-6
IUPAC Nor:
2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
Synonymes:
2-(morpholin-4-yl)-8-phenylchromen-4-one
Poids moléculaire (g/mol):
307.35
Formule moléculaire:
C19H17NO3
InChi Key:
CZQHHVNHHHRRDU-UHFFFAOYSA-N
SMILES:
O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCOCC1
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résultats
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LY 294002, TRC
CAS: 154447-36-6 Formule moléculaire: C19H17NO3 Poids moléculaire (g/mol): 307.34 Synonyme: NSC 697286,SF 1101,8-Phenyl-2-(morpholin-4-yl)-chromen-4-one,2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one,2-Morpholino-8-phenyl-4H-chromen-4-one SMILES: COC(=O)C[C@@H](Br)C(=O)OC
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3
LY294002, MedChemExpress
MedChemExpress LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ and PI3Kβ, respectively. LY294002 also inhibits CK2 with an IC50 of 98 nM. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 μM. LY294002 is an apoptosis activator.
