CAS RN 162042-44-6
CAS RN 162042-44-6
IUPAC Nor:
1-(1-{4-[(1-acetylpiperidin-4-yl)oxy]-2-methoxybenzoyl}piperidin-4-yl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
Synonymes:
1-(1-{4-[(1-acetylpiperidin-4-yl)oxy]-2-methoxybenzoyl}piperidin-4-yl)-4H-3,1-benzoxazin-2-one
Poids moléculaire (g/mol):
507.59
Formule moléculaire:
C28H33N3O6
InChi Key:
WDERJSQJYIJOPD-UHFFFAOYSA-N
SMILES:
COC1=C(C=CC(OC2CCN(CC2)C(C)=O)=C1)C(=O)N1CCC(CC1)N1C(=O)OCC2=CC=CC=C12
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L-371,257, MedChemExpress
MedChemExpress L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM).
