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1,1-Dimethylbiguanide hydrochloride

Código de producto. 15495609
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Código de producto. 15495609 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J63361.14
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Descripción

An antidiabetic agent | CAS: 1115-70-4 | C4H12ClN5 | 165.63 g/mol

1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1

• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes

• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells

• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway

• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders

• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell

TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 1115-70-4
Formule moléculaire C4H12ClN5
Poids moléculaire (g/mol) 165.63
Numéro MDL MFCD00012582
Clé InChI OETHQSJEHLVLGH-UHFFFAOYSA-N
Synonyme metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
CID PubChem 14219
Nom IUPAC hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N

Especificaciones

Nom chimique ou matériau 1,1-Dimethylbiguanide hydrochloride
Point de fusion 218°C to 226°C
Couleur Blanc
Formule linéaire NH2C(=NH)NHC(=NH)N(CH3)2·HCl
Quantité 25 g
Merck Index 14,5938
Informations sur la solubilité Soluble in water (50mg/ml),ethanol,and DMSO (50 mM).
Poids de la formule 165.62
Forme physique Powder

RUO – Research Use Only

Título del producto
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