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  7. 4’,7-dihydroxyisoflavone, 97 %, Thermo Scientific Chemicals

4’,7-dihydroxyisoflavone, 97 %, Thermo Scientific Chemicals

Product Code. 11459927
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Product Code. 11459927 Supplier Thermo Scientific Alfa Aesar Supplier No. B22877.14
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Description

CAS: 486-66-8 | C15H10O4 | 254.241 g/mol

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
La 4′,7-dihydroxyisoflavone est un phytoestrogène qui est censé jouer un rôle dans la prévention des cancers induits par les hormones. Elle protège contre les dommages oxydatifs dans les cellules hépatiques induites par le 7,12-diméthylbenz[a]anthracène (DMBA). L’activité de la catalase et de la superoxyde dismutase, régulée par le DMBA, a été restaurée par la daidzéine.

Solubilité
Insoluble dans l’eau. Soluble dans le DMSO (25 mg/ml), l’éthanol (2 mg/ml), le DMF (10 mg/ml) et 1:10 DMSO:PBS (pH7,2) (0,15 mg/ml).

Remarques
Stable dans les conditions de stockage recommandées. Incompatible avec les agents oxydants et la chaleur.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 486-66-8
Formule moléculaire C15H10O4
Poids moléculaire (g/mol) 254.241
Numéro MDL MFCD00016954
Clé InChI ZQSIJRDFPHDXIC-UHFFFAOYSA-N
Synonyme daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
CID PubChem 5281708
ChEBI CHEBI:28197
Nom IUPAC 7-hydroxy-3-(4-hydroxyphényl)chromén-4-one
SMILES C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

Specifications

Nom chimique ou matériau 4',7-Dihydroxyisoflavone
Point de fusion 328°C to 332°C (decomposition)
Quantité 25 g
Beilstein 231523
Merck Index 14,2801
Informations sur la solubilité Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml).
Poids de la formule 254.24
Pourcentage de pureté 97%

RUO – Research Use Only

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