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Capsazepine, 98+%

Code produit 15415329
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15415329 50 mg 50mg
15405329 10 mg 10mg
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Code produit 15415329 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur J63055.MF
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Expédition estimée: 08-10-2026
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Description

A competitive antagonist for capsaicin and resiniferatoxin | CAS: 138977-28-3 | C19H21ClN2O2S | 376.899 g/mol

Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Solubility
Soluble in ethanol or DMSO

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 138977-28-3
Formule moléculaire C19H21ClN2O2S
Poids moléculaire (g/mol) 376.899
Numéro MDL MFCD00153778
Clé InChI DRCMAZOSEIMCHM-UHFFFAOYSA-N
Synonyme capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
CID PubChem 2733484
ChEBI CHEBI:70773
Nom IUPAC N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
SMILES C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Spécification

Nom chimique ou matériau Capsazepine
Point de fusion 159°C to 161°C
Couleur Blanc
Quantité 50 mg
Informations sur la solubilité Soluble in ethanol or DMSO
Poids de la formule 376.9
Pourcentage de pureté ≥99%
Forme physique Powder

RUO – Research Use Only

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