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Cimetidine, 98+%

Code produit 15475129
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15475129 25 g 25g
15455129 5 g 5g
15465129 10 g 10g
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Code produit 15475129 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur J62825.14
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Description

H2 histamine receptor antagonist | CAS: 51481-61-9 | C10H16N6S | 252.34 g/mol

Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

Solubility
Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 51481-61-9
Formule moléculaire C10H16N6S
Poids moléculaire (g/mol) 252.34
Numéro MDL MFCD00133296
Clé InChI AQIXAKUUQRKLND-UHFFFAOYSA-N
Synonyme cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine
CID PubChem 2756
ChEBI CHEBI:3699
Nom IUPAC 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
SMILES CC1=C(N=CN1)CSCCNC(=NC)NC#N

Spécification

Nom chimique ou matériau Cimetidine
Point de fusion 139°C to 144°C
Couleur Blanc
Quantité 25 g
Merck Index 14,2279
Informations sur la solubilité Soluble to 50 mM in water and to 100 mM in DMSO,solubility in HCl (almost transparency).
Poids de la formule 252.34
Pourcentage de pureté ≥98%
Forme physique Powder

RUO – Research Use Only

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