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cis-4-hydroxy-L-proline, 99 %, Thermo Scientific Chemicals

Product Code. 15483627
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Quantité:
250 mg
1 g
Unit Size:
1g
250mg
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Product Code. 15483627

Brand: Thermo Scientific Alfa Aesar H27194.MD

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Description

CAS: 618-27-9 | C5H9NO3 | 131.13 g/mol

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubilité
Soluble dans l’eau.

Remarques
Stockez-le dans un endroit frais. Garder le récipient bien fermé dans un endroit sec et bien ventilé. Conserver à l’écart des agents oxydants forts.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 618-27-9
Formule moléculaire C5H9NO3
Poids moléculaire (g/mol) 131.13
Numéro MDL MFCD00064319,MFCD00064320
Clé InChI PMMYEEVYMWASQN-IMJSIDKUSA-N
Synonyme cis-4-hydroxy-l-proline, 2s,4s-4-hydroxypyrrolidine-2-carboxylic acid, l-hydroxyproline, l-allohydroxyproline, allo-4-hydroxy-l-proline, cis-4-hydroxyproline, 4s-4-hydroxy-l-proline, l-cis-4-hydroxyproline, l-allo-hydroxyproline, l-proline, 4-hydroxy-, 4s
CID PubChem 440015
ChEBI CHEBI:28397
Nom IUPAC Acide (2S,4S)-4-hydroxypyrrolidine-2-carboxylique
SMILES O[C@@H]1CN[C@@H](C1)C(O)=O

Specifications

Nom chimique ou matériau cis-4-Hydroxy-L-proline
Point de fusion ∽250°C (decomposition)
Informations sur la solubilité Soluble in water.
Quantité 250 mg
Poids de la formule 131.13
Rotation optique −59° (c=2 in Water)
Pourcentage de pureté 99%

RUO – Research Use Only

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