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Deguelin, MedChemExpress

Code produit 16485678
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16485678 10 mg
16451847 50 mg
16418377 5 mg
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Code produit 16485678 Fournisseur Medchem Express Code fournisseur HY13425
 Article restreint
Expédition estimée: 20-11-2026
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Description

MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

Specifications

Nom chimique ou matériau Deguelin
CAS 522-17-8
Couleur Light Yellow
Notes de qualité de la pureté Research
Formule moléculaire C23H22O6
Quantité 10 mg
Synonyme (-)-Deguelin (-)-cis-Deguelin
Informations sur la solubilité DMSO : 100 mg/mL (253.54 mM; Need ultrasonic)
SMILES O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
Poids moléculaire (g/mol) 394.42
Poids de la formule 394.42
Pourcentage de pureté 98.0%
Qualité Research
Forme physique Solid
À utiliser avec (application) Cancer-Kinase/protease
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Research purposes only

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