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Gibco™ Human EPO (Erythropoietin) Recombinant Protein

Code produit 10181193
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Quantité:
500 UI
Conditionnement:
1 pièce
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10181193 500 UI 1 pièce
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Code produit 10181193 Fournisseur Gibco™ Code fournisseur PHC2054

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Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, deionized water to a concentration of 12,000-120,000 IU/mL. Further dilutions can be made in aqueous buffers. For long term storage, EPO solutions should be supplemented with carrier protein, such as 0.1% HSA or BSA. Storage: This lyophilized preparation is stable at room temperature for three weeks, but should be stored desiccated below -18°C. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C, but should be stored below -18°C for long term storage. Avoid repeated freeze/thaw cycles.

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
TRUSTED_SUSTAINABILITY

Spécification

Numéro d’adhésion P01588
À utiliser avec (application) Bioactivity
Formule 0.006mg citric acid, 0.59mg sodium citrate with 0.58mg NaCl and no preservative
Identification génétique (Entrez) 2056
Poids moléculaire 30.4 kDa
Nom Human EPO (Erythropoietin)
Méthode de purification Purified
Quantité 500 UI
Conditions de stockage -20°C
État réglementaire RUO
Concentration en endotoxines <0.1 ng/μg
Alias de gène EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Nom usuel Epo
Symbole de gène(s) EPO
Activité biologique Specific Activity = 150,000 IU/mg; determined by measuring normocythaemic mice.
Type de produit Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Séquence APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR
Contenu et stockage -20°C
Classification Carrier-Free
Activité Specific Activity = 150,000 IU/mg; determined by measuring normocythaemic mice.
Niveau d’endotoxines <0.1 ng/μg
Conditions d’expédition Approved for shipment on Wet or Dry Ice
Système d’expression CHO cells
Famille de protéines Growth Factors & Receptors
Forme protéique Recombinant, Ligand
Forme Lyophilized
Sous-type de protéine EPO
Catégorie de recherche Neurobiology, Stem Cell Research, Differentiation
Gamme de produits Gibco
Pureté ou qualité >98% by SDS-PAGE
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