missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protéines recombinantes
  4. 11588866

Gibco™ Human FGF-basic (FGF-2/bFGF) Recombinant Protein

Code produit 11588866
Change view
Click to view available options
Quantité:
10 μg
Conditionnement:
10µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Code produit Quantité unitSize
11588866 10 μg 10µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.
Code produit 11588866 Fournisseur Gibco™ Code fournisseur 13256029

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!

250.80 EUR valable jusqu'au 2026-04-30
MEILLEUR PRIX promo! Utilisez le code promo "28034" pour bénéficier de cette offre.
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Description

Recombinant Protein

Carrier-Free Reconstitution: Reconstitute in 100 μL of 10 mM Tris, pH 7.6, to yield a stock solution of 0.1 mg/mL of bFGF. To avoid loss due to adsorption, prepare dilute solutions in appropriate assay buffer containing at least 0.1% BSA just prior to use. Do not store in dilute solution. For longer term storage, aliquot into buffer containing 0.1% BSA and store in polypropylene vials at -20°C. Avoid repeated freezing and thawing. In applications requiring long-term use of this growth factor in cell cultures, refilter material after dilution in BSA-containing buffer, through a 0.22 micron low protein-binding filter Storage: Six months at -20°C as received. Up to six months at -20°C when aliquoted into solution containing carrier protein (see Reconstitution Recommendation). NOTE: Do not store in dilute aqueous solution. Avoid repeated freeze/thaw.

FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
TRUSTED_SUSTAINABILITY

Spécification

Numéro d’adhésion P09038
À utiliser avec (application) Bioactivity
Formule Protein with no preservative
Identification génétique (Entrez) 2247
Nom Human FGF-basic (FGF-2/bFGF)
Méthode de purification Purified
Quantité 10 μg
Conditions de stockage -20°C
État réglementaire RUO
Concentration en endotoxines ≤0.1 ng/μg
Alias de gène Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); Fibroblast growth factor basic; HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
Nom usuel FGF2
Symbole de gène(s) FGF2
Activité biologique ED50 < 1.0 ng/mL; determined by the dose-dependent stimulation of BALB/3T3 cells.
Type de produit Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Contenu et stockage -20°C
Classification Carrier-Free
Activité ED50 < 1.0 ng/mL; determined by the dose-dependent stimulation of BALB/3T3 cells.
Niveau d’endotoxines <0.1 ng/μg
Conditions d’expédition Dry Ice
Système d’expression E. coli
Famille de protéines Growth Factors & Receptors
Forme protéique Full Length, Recombinant, Ligand
Forme Lyophilized
Sous-type de protéine FGFs (Fibroblast Growth Factors)
Catégorie de recherche Neurobiology, Oncology, Stem Cell Research, Microbiology, Differentiation, Angiogenesis
Pureté ou qualité ≥95% by SDS-PAGE
Afficher plus Afficher moins
Nom du produit
Sélectionnez un problème

En cliquant sur Soumettre, vous reconnaissez que vous pouvez être contacté par Fisher Scientific au sujet des informations que vous avez fournies dans ce formulaire. Nous ne partagerons pas vos informations à d'autres fins. Toutes les informations de contact fournies seront également conservées conformément à notre politique de confidentialité. Politique de confidentialité.