Invitrogen™ Human MR-ProADM ELISA Kit

MR-proADM, short for mid-regional proadrenomedullin, is a precursor protein that gives rise to the adrenomedullin (ADM) hormone. It is involved in various physiological processes, particularly in the regulation of cardiovascular function and inflammation. Functionally, MR-proADM is associated with vasodilation, blood pressure regulation, and immune response modulation. It acts as a biomarker for endothelial dysfunction and can be used to assess the severity of certain cardiovascular diseases. Elevated levels of MR-proADM have also been linked to systemic inflammation and sepsis. Structurally, MR-proADM is a protein that consists of a chain of amino acids. It undergoes post-translational processing to generate the active form of ADM, which is a shorter peptide consisting of 52 amino acids. Localization-wise, MR-proADM is primarily produced in various tissues, including the adrenal glands, lungs, and endothelial cells lining blood vessels. It is released into the bloodstream and can be measured as a biomarker to provide insight into cardiovascular health and inflammatory conditions.