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Proteintech HumanKine™ recombinant human IL-34 protein

Code produit 17610077 Tous les produits Proteintech Produits
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Code produit 17610077 Fournisseur Proteintech Code fournisseur HZ1316100UG

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Description

HumanKine™ recombinant protein

IL-34 is a 6-α-helix, proinflammatory cytokine that serves as a ligand for colony-stimulating factor-1 receptor (CSF1R). It is expressed most abundantly by spleen cells. It primarily stimulates human peripheral blood monocyte proliferation and macrophage colony formation. It is also required for Langerhans cell and microglia development. IL-34 has been shown to play a protective role in cancer and Alzheimer’s disease, but it can promote the progression of several autoimmune, inflammatory, and metabolic diseases. As such IL-34 could be used as a biomarker to mark the progression of these diseases (PMID: 22579672, 27577879, 31940023).

Spécification

Numéro d’adhésion Q6ZMJ4
Formule 50 mM Acetate pH 4.5 + 75 mM NaCl, See Certificate of Analysis for details
Identification génétique (Entrez) 146433
Poids moléculaire 68 and 38 kDa
Quantité 100 μg
Source HEK293
Conditions de stockage Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
Concentration en endotoxines <1 EU/μg
Réactivité spécifique Human
Recombinant Recombinant
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Forme Lyophilized
Pureté ou qualité >95%
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