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  7. Hydroxyurée, 98 %, Thermo Scientific Chemicals

Hydroxyurée, 98 %, Thermo Scientific Chemicals

Code produit 11469782
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Product Code. 11469782 Supplier Thermo Scientific Alfa Aesar Supplier No. A10831.03
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Description

CAS: 127-07-1 | CH4N2O2 | 76.055 g/mol

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubilité
Soluble dans l’eau, l’alcool chaud et le diméthylsulfoxyde. Insoluble dans l’éthanol et le benzène.

Remarques
Sensible à l’humidité. Stockez-le dans un endroit frais. Gardez le récipient hermétiquement fermé dans un endroit sec et bien ventilé. Incompatible avec les agents oxydants forts.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 127-07-1
Formule moléculaire CH4N2O2
Poids moléculaire (g/mol) 76.055
Numéro MDL MFCD00007943
Clé InChI VSNHCAURESNICA-UHFFFAOYSA-N
Synonyme hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid
CID PubChem 3657
ChEBI CHEBI:44423
Nom IUPAC Hydroxyurée
SMILES C(=O)(N)NO

Specifications

Nom chimique ou matériau Hydroxyurea
Point de fusion ∽140°C (decomposition)
Plage de pourcentage du dosage 98%
Quantité 1 g
Beilstein 1741548
Informations sur la solubilité Soluble in water,hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Poids de la formule 76.06

Safety and Handling

compliance-icons
Product Identifier
  • Hydroxyurea
 Signal Word
  • Dangers
 Hazard Category
  • Mutagénicité des cellules germinales Catégorie 1B
  • Toxicité pour la reproduction Catégorie 1A
 Hazard Statement
  • H340-Peut induire des anomalies génétiques.
  • H360D-Peut nuire au foetus.
 Precautionary Statement
  • P201-Se procurer les instructions avant utilisation.
  • P308+P313-EN CAS d'exposition prouvée ou suspectée: consulter un médecin.
 Supplemental information
  • MIXTURE LIST-Contain: Hydroxyurea

RUO – Research Use Only

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