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Isatine, 98 %, Thermo Scientific Chemicals

Code produit. 11494064
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Product Code. 11494064

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CAS: 91-56-5 | C8H5NO2 | 147.133 g/mol

Isatin is an endogenous monoamine oxidize (MAO) inhibitor involved in stress and anxiety. Additionally, isatin inhibits alkaline phosphatase (ALP), nitric oxide (NO)-stimulated soluble guanylate cyclase, and other enzymes. Isatins undergo a one-pot Wolff-Kishner like reduction with hydrazine hydrate, under surprisingly mild conditions, to give the corresponding oxindoles. It is used as chromatographic spray reagent for amino acid detection.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L’isatine est un inhibiteur endogène de la monoamine oxydase (MAO) à l’origine du stress et de l’anxiété. En outre, l’isatine inhibe la phosphatase alcaline (ALP), la guanylate cyclase soluble stimulée par l’oxyde nitrique (NO) et d’autres enzymes. Les isatines subissent une réduction de Wolff-Kishner monotope avec de l’hydrate d’hydrazine, dans des conditions étonnamment douces, pour donner les oxindoles correspondants. Il est utilisé comme réactif de pulvérisation chromatographique pour la détection des acides aminés.

Solubilité
Soluble dans l’eau (1,9 g/l à 20°C).

Remarques
Stocker dans un endroit frais et sec. Veiller à une ventilation correcte. Incompatible avec les agents oxydants.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 91-56-5
Formule moléculaire C8H5NO2
Poids moléculaire (g/mol) 147.133
Numéro MDL MFCD00005718
Clé InChI JXDYKVIHCLTXOP-UHFFFAOYSA-N
Synonyme isatin, indoline-2,3-dione, 2,3-indolinedione, indole-2,3-dione, isatine, 2,3-dioxoindoline, pseudoisatin, tribulin, isotin, isatic acid lactam
CID PubChem 7054
ChEBI CHEBI:27539
Nom IUPAC 1H-indole-2,3-dione
SMILES C1=CC=C2C(=C1)C(=O)C(=O)N2

Specifications

Nom chimique ou matériau Isatin
Point de fusion ∼199°C to 200°C
pH 7
Point d’éclair 220°C (428°F)
Odeur Odorless
Quantité 100 g
Beilstein 383659
Merck Index 14,5104
Informations sur la solubilité Soluble in water (1.9g/L at 20°C).
Poids de la formule 147.13
Pourcentage de pureté 98%
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