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Gibco™ Mouse CCL21 (6Ckine) Recombinant Protein

Code produit 10513965
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Quantité:
20 μg
Conditionnement:
1 pièce
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Code produit Quantité unitSize
10513965 20 μg 1 pièce
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Code produit 10513965 Fournisseur Gibco™ Code fournisseur PMC1474

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Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute this protein in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA. Storage: This lyophilized preparation is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -80°C for 3months. Avoid repeated freeze/thaw cycles.

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
TRUSTED_SUSTAINABILITY

Spécification

Numéro d’adhésion P84444, P86792, P86793
À utiliser avec (application) Bioactivity
Formule Protein with no preservative
Identification génétique (Entrez) 100042493, 18829, 65956
Poids moléculaire 12 kDa
Nom Mouse CCL21 (6Ckine)
Méthode de purification Purified
Quantité 20 μg
Conditions de stockage -20°C
État réglementaire RUO
Concentration en endotoxines <0.1 ng/μg
Alias de gène 6 Ckine; 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21A (serine); chemokine (C-C motif) ligand 21B (leucine); chemokine (C-C motif) ligand 21b (serine); chemokine (C-C motif) ligand 21C (leucine); chemokine CCL21/6CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600
Nom usuel CCL21
Symbole de gène(s) Ccl21a, Ccl21b, Ccl21c
Activité biologique ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human activated T-cells in the presence of IL-2.
Type de produit Protein
Conjugué Unconjugated
Espèces Mouse
Recombinant Recombinant
Séquence Mouse CCL21 recombinant protein contains 110 amino acids
Contenu et stockage -20°C
Classification Carrier-Free
Activité ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human activated T-cells in the presence of IL-2.
Niveau d’endotoxines <0.1 ng/μg
Conditions d’expédition Approved for shipment on Wet or Dry Ice
Système d’expression E. coli
Famille de protéines Chemokines & Receptors
Forme protéique Recombinant, Ligand
Forme Lyophilized
Sous-type de protéine 6 CKINE
Catégorie de recherche Immunology
Gamme de produits Gibco
Pureté ou qualité ≥98% by SDS-PAGE and HPLC
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