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Nitrofurantoïne, 98 %, Thermo Scientific Chemicals

Code produit 11441077
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Code produit 11441077 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur B24079.36
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Description

CAS: 67-20-9 | C8H6N4O5 | 238.16 g/mol

Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.

Solubility
Soluble in water (<0.01g/100mL at 19°C), dimethyl sulfoxide and methanol.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Store under dry inert gas. It is hygroscopic in nature. Incompatible with oxidizing agents. It is sensitive to light.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 67-20-9
Formule moléculaire C8H6N4O5
Poids moléculaire (g/mol) 238.16
Numéro MDL MFCD00003224
Clé InChI NXFQHRVNIOXGAQ-YCRREMRBSA-N
Synonyme nitrofurantoin, macrodantin, 5-nitrofurantoin, furadantin, furadonine, nitrofurantoine, furadantine, furadantoin, furadoine, furadontin
CID PubChem 6604200
ChEBI CHEBI:71415
Nom IUPAC 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione
SMILES [O-][N+](=O)C1=CC=C(O1)\C=N\N1CC(=O)NC1=O

Spécification

Nom chimique ou matériau Nitrofurantoin
Point de fusion ∼265°C (decomposition)
Quantité 500 g
Sensibilité Hygroscopic; Light sensitive
Informations sur la solubilité Soluble in water (<0.01g/100 ml at 19°C),dimethyl sulfoxide and methanol.
Poids de la formule 238.16
Pourcentage de pureté 98%

RUO – Research Use Only

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