Gibco™ PeproGMP™ Human IL-6 Recombinant Protein, PeproTech®

Recombinant Protein

The IL-6 protein is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. The PeproTech Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. PeproGMP IL-6 cytokine is most often used with PeproGMP SCF, PeproGMP TPO (thrombopoietin) and PeproGMP Flt3-ligand in hematopoietic stem cells (HSCs) cultures. IL-3 may also be used for further synergistic expansion and immune cell maturation. PeproGMP Recombinant Human IL-6 is also commonly used with PeproGMP IL-2 and PeproGMP IL-15 for B cell cultures. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the Certificate of Analysis. All PeproGMP™ products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.