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Gibco™ PeproGMP® Human VEGF-165 Recombinant Protein, PeproTech®

Code produit 30275722
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Quantité:
1 mg
100 μg
50 μg
Conditionnement:
100µg
1mg
50µg
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Code produit Quantité unitSize
30275722 1 mg 1mg
30275491 100 μg 100µg
30275000 50 μg 50µg
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Code produit 30275722 Fournisseur Gibco™ Code fournisseur GMP100201MG

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Description

Recombinant Protein

Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Additional product information and specifications are provided on the Certificate of Analysis. All PeproGMP® products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products. Product use statement: For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
TRUSTED_SUSTAINABILITY

Spécification

Numéro d’adhésion P15692
À utiliser avec (application) Control, Western Blot Control, Bioactivity
Format Lyophilized
Formule Protein with no preservative
Identification génétique (Entrez) 7422
Poids moléculaire 38.2 kDa
Nom PeproGMP™ Human VEGF-165
Méthode de purification Purified
Quantité 1 mg
Conditions de stockage -20°C or -80°C if preferred
État réglementaire GMP
Concentration en endotoxines ≤0.1 EU/μg
Alias de gène H-VEGF-165; MVCD1; M-VEGF-165; vascular endothelial growth factor 165b; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular permeability factor; VEGF; VEGF164; VEGF165; Vegfa; VEGF-A; VPF
Nom usuel VEGF-165
Symbole de gène(s) Vegfa
Activité biologique Determined by the proliferation of HUVECs.
Type de produit Protein
Conjugué Unconjugated
Recombinant Recombinant
Séquence APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Contenu et stockage -20°Cor to +80°C if preferred
Activité Determined by the proliferation of HUVECs.
Système d’expression E. coli
Forme Lyophilized
Gamme de produits PeproGMP
Pureté ou qualité ≥ 98% by SDS-PAGE gel and HPLC analyses.
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