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PTC299, MedChemExpress

Code produit 16497897
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16497897 5 mg
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Product Code. 16497897 Supplier Medchem Express Supplier No. HY124593

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Description

MedChemExpress PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.

PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies.

Specifications

Nom chimique ou matériau PTC299
CAS 1256565-36-2
Couleur Blanc
Notes de qualité de la pureté Research
Formule moléculaire C25H20Cl2N2O3
Quantité 5 mg
Informations sur la solubilité DMSO : 50 mg/mL (106.99 mM; Need ultrasonic)
SMILES O=C(N([C@H]1C2=CC=C(OC)C=C2)CCC3=C1NC4=C3C=C(Cl)C=C4)OC5=CC=C(Cl)C=C5
Poids moléculaire (g/mol) 467.34
Poids de la formule 467.34
Pourcentage de pureté 98.24%
Qualité Research
Forme physique Solid
À utiliser avec (application) Cancer-Kinase/protease
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Research purposes only

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