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Talmapimod, MedChemExpress

Artikelnummer. p-200100866
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16443948 10 mg
16432926 25 mg
16426667 5 mg
16400307 50 mg
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Product Code. 16443948 Supplier Medchem Express Supplier No. HY10406

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Description

MedChemExpress Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Specifications

Nom chimique ou matériau Talmapimod
CAS 309913-83-5
Couleur Rose
Notes de qualité de la pureté Research
Formule moléculaire C27H30ClFN4O3
Quantité 10 mg
Synonyme SCIO-469
Informations sur la solubilité DMSO : ≥ 100 mg/mL (194.93 mM)
SMILES O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[C@H](C)CN(CC4=CC=C(F)C=C4)[C@@H](C)C3)=O)C(Cl)=C2)=O
Poids moléculaire (g/mol) 513.0
Poids de la formule 513.0
Pourcentage de pureté 98.04%
Qualité Research
Forme physique Solid
À utiliser avec (application) Cancer-Kinase/protease
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Research purposes only

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