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  5. Tocris Bioscience™ TC ASK 10

Tocris Bioscience™ TC ASK 10
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Code produit 30001633
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10 mg
50 mg
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50mg
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Product Code. Quantité unitSize
30001633 50 mg 50mg
30001618 10 mg 10mg
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Product Code. 30001633 Supplier Tocris Bioscience™ Supplier No. 4825/50

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Description

Potent and selective ASK1 inhibitor; orally bioavailable

Potent ASK1 inhibitor (IC50 = 14 nM); displays selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 values are > 10 μM). Blocks downstream JNK1/p38 phosphorylation in cells. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1005775-56-3
Formule moléculaire C21H23Cl2N5O

Specifications

Nom chimique ou matériau TC ASK 10
Quantité 50 mg
Poids de la formule 432.35
Pureté >98%
Poids moléculaire 432.349
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