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  8. Thapsigargine, 95 %, Thermo Scientific Chemicals

Thapsigargine, 95 %, Thermo Scientific Chemicals

Product Code. 15445169
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Product Code. 15445169 Supplier Thermo Scientific Alfa Aesar Supplier No. J62866.MA
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Description

CAS: 67526-95-8 | C34H50O12 | 650.76 g/mol

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
La thapsigargine- induit une régulation du récepteur de l’EGF, indépendamment de l’activation de la protéine kinase C. Elle est également utilisée comme inducteur de la libération de Ca2+ stockée.

Solubilité
Soluble dans le DMSO (20 mg/ml), l’éthanol (20 mg/ml) et l’acétone.

Remarques
Stockez-le dans un endroit frais. Garder le récipient bien fermé dans un endroit sec et bien ventilé. Température de stockage recommandée : -20°C.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 67526-95-8
Formule moléculaire C34H50O12
Poids moléculaire (g/mol) 650.76
Numéro MDL MFCD00083511
Clé InChI IXFPJGBNCFXKPI-FSIHEZPISA-N
CID PubChem 126969181
SMILES CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(C)=O)[C@@H]12)OC(=O)CCC

Specifications

Nom chimique ou matériau Thapsigargin
Couleur Blanc
Quantité 10 mg
Sensibilité Light sensitive
Merck Index 14,9272
Synonyme thapsigargin, unii-z96bq26rzd, z96bq26rzd, chembl96926, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid, 6-acetyloxy-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy azuleno 4,5-b furan-7-yl ester, 3s-3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha z ,9balpha, tg1, --thapsigargin, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid 3s-3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester
Informations sur la solubilité Soluble in DMSO (20mg/ml),ethanol (20mg/ml),and acetone.
Nom IUPAC Octanoate de [(3S,3aR,4S,6S,6aS,7S,8S,9bR)-6-acétyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-triméthyl-8-(2-méthylbut-2-énoyloxy)-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl]
Poids de la formule 650.75
Pourcentage de pureté 95%
Forme physique Film solide
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