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Thiamphenicol

Code produit 15495769
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5 g
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Code produit Quantité Conditionnement
15495769 5 g 5g
15485769 1 g 1g
15405779 25 g 25g
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Code produit 15495769 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur J63575.06
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Description

The methyl-sulfonyl analogue of chloramphenicol | CAS: 15318-45-3 | C12H15Cl2NO5S | 356.214 g/mol

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 15318-45-3
Formule moléculaire C12H15Cl2NO5S
Poids moléculaire (g/mol) 356.214
Numéro MDL MFCD00467983
Clé InChI OTVAEFIXJLOWRX-NXEZZACHSA-N
Synonyme thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
CID PubChem 27200
ChEBI CHEBI:32215
Nom IUPAC 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
SMILES CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O

Specifications

Nom chimique ou matériau Thiamphenicol
Couleur Blanc à jaune
Quantité 5 g
Beilstein 2819542
Merck Index 14,9301
Informations sur la solubilité Soluble in acetonitrile or DMF; Slightly soluble in water
Poids de la formule 356.22
Forme physique Powder

RUO – Research Use Only

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