CAS RN 1197196-48-7
CAS RN 1197196-48-7
IUPAC Nor:
7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Synonymes:
7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Poids moléculaire (g/mol):
485.68
Formule moléculaire:
C26H43N7O2
InChi Key:
XIVUGRBSBIXXJE-UHFFFAOYSA-N
SMILES:
COC1=CC2=C(NC3CCN(C)CC3)N=C(N=C2C=C1OCCCN(C)C)N1CCCN(C)CC1
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résultats
1
Tocris Bioscience™ UNC 0224
CAS: 1197196-48-7 Formule moléculaire: C26H43N7O2
2
UNC0224, MedChemExpress
MedChemExpress UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6 nM, an IC50 of 15 nM and a Kd of 23 nM. UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58 nM. UNC0224 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.
