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  5. Tocris Bioscience™ AZ 10397767

Tocris Bioscience™ AZ 10397767
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Product Code. 18777686
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Quantité:
10 mg
50 mg
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10mg
50mg
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Product Code. 18777686

missing translation for 'mfr': Tocris Bioscience™ 5872/10

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Description

Potent CXCR2 antagonist

AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

CAS 333742-63-5
Quantité 10 mg
Cible Chemokine Receptor
Formule moléculaire C15H14ClFN4O2S2
Poids de la formule 400.88g/mol
Type de produit Antagonist

Usage exclusivement réservé à la recherche

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