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Invitrogen™ Human CDK18/cyclin Y, GST Tag Recombinant Protein

Product Code. 15980273
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Quantité:
1 mg
10 μg
100 μg
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100µg
10µg
1mg
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Product Code. 15980273

missing translation for 'mfr': Invitrogen™ A30492

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This CDK18/cyclin Y recombinant human protein (CDK18: full length, cyclin Y: 2-end) was expressed in insect cells. CDK18/cyclin Y recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for CDK18/cyclin Y are AAH11526 and NP_659449.3.

CDK18/cyclin Y serine/threonine kinase or cyclin-dependent kinase 18 belongs to the cdc2/cdkx subfamily of kinases. CDK18/cyclin Y is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2. CDK18/cyclin Y is expressed in a variety of human cell lines and tissues. Elevation in the protein levels of CDK18/cyclin Y in the temporal cortex of Alzheimer's disease relative to control brains has been observed. It is proposed that CDK18/cyclin Y is a paired helical filaments-associated kinase that modulates tau phosphorylation.
TRUSTED_SUSTAINABILITY

Specifications

Numéro d’adhésion Q07002
Concentration See Label
À utiliser avec (application) Kinase Assay
Formule 50mM tris HCl with 25% glycerol, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 150mM NaCl, 0.25mM DTT and no preservative; pH 7.5
Identification génétique (Entrez) 5129
Poids moléculaire 80.5-65.5 kDa
Nom Human CDK18/cyclin Y, GST Tag
Plage de pH 7.5
Méthode de purification Purified
Quantité 10 μg
Conditions de stockage -80°C, Avoid Freeze/Thaw Cycles
État réglementaire RUO
Alias de gène PCTK3
Nom usuel CDK18
Symbole de gène(s) CDK18
Famille des kinases CDKs and CHKs
Type de produit Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Marqueur de protéine GST-tag
Séquence CDK18: Full Length, Cyclin Y: 2-341
Contenu et stockage -80°C, Avoid Freeze/Thaw Cycles
Conditions d’expédition Dry Ice
Système d’expression Insect cells
Famille de protéines Kinases & Inhibitors
Forme protéique Recombinant, Active, Catalytic
Forme Liquid
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