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Invitrogen™ Human CDK2/Cyclin A, His Tag Recombinant Protein
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Quantité:
1 mg
10 μg
100 μg
Conditionnement:
100µg
10µg
1mg
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.
CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
Spécification
Spécification
| Numéro d’adhésion | P24941 |
| Concentration | See Label |
| À utiliser avec (application) | Kinase Assay |
| Formule | 20mM tris with 2mM DTT, 150mM NaCl, 0.5mM EDTA, 0.01% Triton X-100, 20% glycerol and no preservative; pH 7.5 |
| Identification génétique (Entrez) | 1017 |
| Poids moléculaire | 91.3 kDa |
| Nom | Human CDK2/Cyclin A, His Tag |
| Plage de pH | 7.5 |
| Méthode de purification | Purified |
| Quantité | 1 mg |
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