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  5. Tocris Bioscience™ Ceritinib

Tocris Bioscience™ Ceritinib
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Code produit. p-7166815
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Quantité:
10 mg
50 mg
Conditionnement:
10mg
50mg
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Code produit. 18706406

Marque: Tocris Bioscience™ 6905/10

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Description

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

Ceritinib is a highly potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 0.2 nM). Also displays potent inhibition of insulin receptor (IR), insulin-like growth factor receptor 1 (IGF1R), serine/threonine-protein kinase STK22D and FLT3 (IC50 values are 7, 8, 23 and 60 nM, respectively). Inhibits tumor growth in Karpas299 and H2228 rat xenograft models.
TRUSTED_SUSTAINABILITY

Spécification

Synonyme LDK378
Quantité 10 mg
Formule moléculaire C28H36ClN5O3S
Poids de la formule 558.14
Type de produit Inhibitor
Pureté 98%
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