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  6. TdB Labs AB Dextran Sulfate High Sulfate Pharma Grade

TdB Labs AB Dextran Sulfate High Sulfate Pharma Grade

Code produit. 30216405
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Poids moléculaire:
5 kDa
8 kDa
Quantité:
10 g
100 g
Conditionnement:
100g
10g
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Code produit. 30216405

Marque: TdB Labs AB DS5 HS PG_10g

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Description

Dextran sulfate is a highly sulfated, low bioburden polymer used in cell media for clinical production. It supports CHO cell viability, reduces aggregation, and enhances protein yield in biopharmaceutical processes.

  • Product Overview: Dextran sulfate Pharma Grade is a high-purity, highly sulfated polysaccharide manufactured with strict quality controls for biopharmaceutical applications. Available in 5 kDa, 8 kDa, and 10 kDa molecular weights, it undergoes extended testing for bioburden, endotoxins, residual solvents, and heavy metals, making it suitable for use in cell culture media, viral clearance studies, and protein stabilization workflows.
  • Features:
    • Pharmaceutical Grade Quality: Produced under stringent quality standards with thorough testing for bioburden, endotoxin, heavy metals, and residual solvents.
    • Highly Sulfated: Provides strong negative charge density critical for interactions with proteins, viral particles, and cellular components.
    • Controlled Molecular Weights: Precisely manufactured in 5 kDa, 8 kDa, and 10 kDa grades to meet diverse application requirements.
    • Water-Soluble: Fully dissolves in aqueous media for easy preparation and integration into cell culture, analytical, or production processes.
    • Batch-to-Batch Consistency: Tight process control ensures reliable performance for regulated or preclinical applications.
  • Benefits:
    • Supports CHO Cell Culture Optimization: Enhances growth and viability in chemically defined and serum-free media for biologics production.
    • Facilitates Viral Clearance Studies: Strong viral binding properties make it valuable in spike removal and clearance validation studies for biologics manufacturing.
    • Consistency for Process Development: Pharmaceutical-grade specifications reduce variability and risk in bioprocess optimization.
    • Safe for Sensitive Applications: Low bioburden and endotoxin levels allow safe use in cell-based research, assay development, and process scale-up.
    • Flexible Application Fit: Available in multiple molecular weights to fine-tune interactions and optimize culture or assay performance.
  • Applications:
    • Cell Culture Media Supplementation: Used in mammalian cell cultures, especially CHO, to enhance cell performance during biologic production.
    • Viral Clearance Studies: Applied in model systems for validating viral removal during biopharmaceutical production processes.
    • Protein Stabilization: Helps prevent aggregation and degradation of therapeutic proteins and enzymes.
    • Bioprocess and Formulation Research: Used in the development of stable, high-performance bioprocesses and formulations for preclinical and early clinical work.
  • Technical Specifications:
    • Molecular Weights: 5 kDa, 8 kDa, and 10 kDa available for specific performance requirements.
    • Sulfation Level: Typically 16 to 20% sulfur content, depending on grade.
    • Purity: Extensively tested for bioburden, endotoxins, and residual solvents according to internal pharma-grade specifications.
    • Appearance: White to off-white powder, readily soluble in water.
  • Storage and Stability:
    • Store dry in a sealed container at ambient temperature.
    • Protect from moisture and light to maintain stability and performance characteristics.
  • Packaging and Availability:
    • Supplied as a dry powder.
    • Available in multiple pack sizes to support research, process development, and scale-up manufacturing needs.

Spécification

Forme Crystalline powder
Type de produit CHO Media Supplement
Stérilité Non-sterile
Quantité 10 g
Poids moléculaire 5 kDa
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