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Human FRAP1 (mTOR), GST Tag Recombinant Protein
Human FRAP1 (mTOR), GST Tag Recombinant Protein
Marque: Invitrogen PV4753
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Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
Spécification
| NP_004949.1 | |
| 163.9 kDa | |
| FRAP1 (mTOR) | |
| aa 1360-2549 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
| Ser⁄Thr Kinases: Atypical | |
| LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™ | |
| FK506 binding protein 12-rapamycin associated protein 1 | |
| Kinases & Inhibitors | |
| Liquid | |
| Signal Transduction, Drug Development, Oncology |
| Kinase Assay | |
| 10 μg | |
| PIKK Kinase Family | |
| Human | |
| GST Tag | |
| Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
| Dry Ice | |
| mTOR, FRAP1 | |
| Baculovirus | |
| Recombinant, Catalytic | |
| Serine/Threonine Kinases |
For Research Use Only. Not for use in diagnostic procedures.