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Invitrogen™ Human FRAP1 (mTOR), GST Tag Recombinant Protein

Code produit. 10012913
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Quantité:
10 μg
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1 pièce
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Código de producto. 10012913

missing translation for 'mfr': Invitrogen™ PV4753

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™.

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
TRUSTED_SUSTAINABILITY

Especificaciones

Numéro d’adhésion P42345
Concentration See Label
À utiliser avec (application) Kinase Assay
Formule 50mM tris with 150mM NaCl, 2mM DTT, 0.1% polysorbate 20, 50% glycerol, 0.5mM EDTA and no preservative; pH 7.5
Identification génétique (Entrez) 2475
Poids moléculaire 163.9 kDa
Nom Human FRAP1 (mTOR), GST Tag
Plage de pH 7.5
Méthode de purification Purified
Quantité 10 μg
Conditions de stockage -80°C, Avoid Freeze/Thaw Cycles
État réglementaire RUO
Alias de gène 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
Nom usuel mTOR
Symbole de gène(s) MTOR
Famille des kinases PIKK Kinase Family
Longueur des protéines 1360-2549
Type de produit Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Marqueur de protéine GST-tag
Séquence 1360-2549
Contenu et stockage -80°C, Avoid Freeze/Thaw Cycles
Entrée du dosage Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Groupe de kinases Ser⁄Thr Kinases: Atypical
Conditions d’expédition Dry Ice
Compatibilité des systèmes LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Entrée cible mTOR, FRAP1
Gène cible FK506 binding protein 12-rapamycin associated protein 1
Système d’expression Insect cells
Famille de protéines Kinases & Inhibitors
Forme protéique Recombinant, Catalytic
Forme Liquid
Sous-type de protéine Serine/Threonine Kinases
Catégorie de recherche Signal Transduction, Drug Development, Oncology
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