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Invitrogen™ Human GSK-3B (GSK3 beta), His Tag Recombinant Protein
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Quantité:
1 mg
10 μg
Conditionnement:
10µg
1mg
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
Spécification
Spécification
| Numéro d’adhésion | P49841 |
| Concentration | See Label |
| À utiliser avec (application) | Kinase Assay |
| Formule | 50mM tris with 150mM NaCl, 0.01% Triton X-100, 2mM DTT, 50% glycerol, 0.5mM EDTA and no preservative; pH 7.5 |
| Identification génétique (Entrez) | 2932 |
| Poids moléculaire | 53.1 kDa |
| Nom | Human GSK-3B (GSK3 beta), His Tag |
| Plage de pH | 7.5 |
| Méthode de purification | Purified |
| Quantité | 10 μg |
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