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Gibco™ Human 4-1BB Receptor Recombinant Protein, PeproTech®
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Quantité:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Conditionnement:
100µg
1mg
20µg
250µg
500µg
5µg
Description
Recombinant Human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine-rich TNFR-like extracellular domain of 4-1BB Receptor. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
Spécification
Spécification
| Numéro d’adhésion | Q07011 |
| À utiliser avec (application) | ELISA, Functional Assay, Western Blot |
| Formule | protein with no preservative |
| Identification génétique (Entrez) | 3604 |
| Poids moléculaire | 17.7 kDa |
| Nom | Human 4-1 BB Receptor |
| Quantité | 100 μg |
| Source | E. coli |
| État réglementaire | RUO |
| Concentration en endotoxines | <1 EU/ μg |
| Afficher plus |
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