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Gibco™ Human CCL2 (MCP-1) Recombinant Protein, PeproTech®

Code produit. p-7246377
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Quantité:
1 mg
100 μg
20 μg
250 μg
5 μg
50 μg
500 μg
Conditionnement:
100µg
1mg
20µg
250µg
500µg
50µg
5µg
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Code produit. 17811753

Marque: Gibco™ 30004100UG

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Description

Recombinant Protein

Recombinant Human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
TRUSTED_SUSTAINABILITY

Spécification

Numéro d’adhésion P13500
À utiliser avec (application) ELISA, Functional Assay, Western Blot
Formule protein with no preservative
Identification génétique (Entrez) 6347
Poids moléculaire 8.6 kDa
Nom Human CCL2 (MCP-1)
Quantité 100 μg
Source E. coli
État réglementaire RUO
Concentration en endotoxines <1 EU/ μg
Alias de gène Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1 A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1 A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Nom usuel CCL2 (MCP-1)
Symbole de gène(s) Ccl2
Activité biologique Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml
Conjugué Unconjugated
Recombinant Recombinant
Séquence QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Contenu et stockage -20°C
Système d’expression E. coli
Forme Lyophilized
Pureté ou qualité ≥ 98% by SDS-PAGE gel and HPLC analyses.
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